MRI contrast agents : from molecules to particles /

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Bibliographic Details
Author / Creator:Laurent, Sophie, 1967- author.
Imprint:Singapore : Springer Singapore : Imprint : Springer, 2017.
©2017
Description:1 online resource (vii, 125 pages : 63 illustrations, 44 illustrations in color)
Language:English
Series:SpringerBriefs in Applied Sciences and Technology, 2191-530X
SpringerBriefs in applied sciences and technology,
Subject:
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/11268946
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Other authors / contributors:Henoumont, Céline, author.
Stanicki, Dimitri, author.
Boutry, Sébastien, author.
Lipani, Estelle, author.
Belaid, Sarah, author.
Muller, Robert N., author.
Vander Elst, Luce, author.
ISBN:9789811025297
9811025290
9789811025273
9811025274
9811025274
Digital file characteristics:text file PDF
Notes:Includes bibliographical references.
Summary:This book describes the multiple aspects of (i) preparation of the magnetic core, (ii) the stabilization with different coatings, (iii) the physico-chemical characterization and (iv) the vectorization to obtain specific nanosystems. Several bio-applications are also presented in this book. In the early days of Magnetic Resonance Imaging (MRI), paramagnetic ions were proposed as contrast agents to enhance the diagnostic quality of MR images. Since then, academic and industrial efforts have been devoted to the development of new and more efficient molecular, supramolecular and nanoparticular systems. Old concepts and theories, like paramagnetic relaxation, were revisited and exploited, leading to new scientific tracks. With their high relaxivity payload, the superparamagnetic nanoparticles are very appealing in the context of molecular imaging but challenges are still numerous: absence of toxicity, specificity, ability to cross the biological barriers, etc.
Other form:Printed edition: 9789811025273
Standard no.:10.1007/978-981-10-2529-7