Hidden Bibliographic Details
| Other authors / contributors: | Duggirala, Ravindranath, editor.
Almasy, Laura, editor.
Williams-Blangero, Sarah, editor.
Paul, Solomon F. D., editor.
Kole, Chittaranjan, editor.
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| ISBN: | 9783662463062
3662463067
3662463059
9783662463055
9783662463055
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| Notes: | Includes bibliographical references and index.
Online resource; title from PDF title page (EBSCO, viewed April 1, 2015).
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| Summary: | This book provides an introduction to the latest gene mapping techniques and their applications in biomedical research and evolutionary biology. It especially highlights the advances made in large-scale genomic sequencing. Results of studies that illustrate how the new approaches have improved our understanding of the genetic basis of complex phenotypes including multifactorial diseases (e.g., cardiovascular disease, type 2 diabetes, and obesity), anatomic characteristics (e.g., the craniofacial complex), and neurological and behavioral phenotypes (e.g., human brain structure and nonhuman primate behavior) are presented. Topics covered include linkage and association methods, gene expression, copy number variation, next-generation sequencing, comparative genomics, population structure, and a discussion of the Human Genome Project. Further included are discussions of the use of statistical genetic and genetic epidemiologic techniques to decipher the genetic architecture of normal and disease-related complex phenotypes using data from both humans and non-human primates.
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| Other form: | Printed edition: 9783662463055
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| Standard no.: | 10.1007/978-3-662-46306-2
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