Vitamin D : physiology, molecular biology, and clinical applications /

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Bibliographic Details
Edition:2nd ed.
Imprint:[Totowa] : Humana, c2010.
Description:1 online resource (xxvi, 1155 p.) : ill.
Language:English
Series:Nutrition and health
Nutrition and health (Totowa, N.J.)
Subject:Vitamin D -- Physiological effect.
Vitamin D -- Therapeutic use.
Vitamin D deficiency.
Vitamin D -- physiology.
Vitamin D -- pharmacology.
Vitamin D -- therapeutic use.
Health.
Vitamin D deficiency.
Vitamin D -- Physiological effect.
Vitamin D -- Therapeutic use.
Electronic books.
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/8893154
Hidden Bibliographic Details
Other authors / contributors:Holick, M. F. (Michael F.)
ISBN:9781603273039
1603273034
9781603273008 (hardcover : alk. paper)
160327300X (hardcover : alk. paper)
Notes:Includes bibliographical references and index.
Description based on print version record.
Summary:In Vitamin D: Physiology, Molecular Biology, and Clinical Applications, Second Edition, leading researchers provide a comprehensive, highly readable overview of the biological functions and clinical applications of vitamin D and its metabolites. Topics range from the most recent recommendations for vitamin D intake to new approaches for the treatment and prevention of vitamin D deficiency and the development of active vitamin D drugs to treat psoriasis and cancer. The book demonstrates the significant role that vitamin D has in maintaining good bone health and the prevention of osteoporosis, a.
Other form:Print version: Vitamin D. 2nd ed. Totowa, N.J. : Humana, 2010 9781603273008 160327300X
Table of Contents:
  • Vitamin D and health: evolution, biologic functions, and recommended dietary intakes for vitamin D
  • Photobiology of vitamin D
  • The functional metabolism and molecular biology of vitamin D action
  • Metabolism and catabolism of vitamin D, its metabolites and clinically relevant analogs
  • The molecular biology of the vitamin D receptor
  • VDR and RXR subcellular trafficking
  • Mechanism of action of 1,25-dihydroxyvitamin D3 on intestinal calcium absorption and renal calcium transport
  • Biological and molecular effects of vitamin D on bone
  • Biological and molecular effects of vitamin D on the kidney
  • Vitamin D and the parathyroids
  • Diversity of vitamin D target genes
  • Extrarenal synthesis of 1,25-dihydroxyvitamin D and its health implications
  • Vitamin D and the innate immunity
  • Vitamin D and colon cancer
  • Mechanisms of resistance to vitamin D action in human cancer cells
  • Vitamin D and the brain: a neuropsychiatric perspective
  • Vitamin D modulation of adipocyte function
  • Determinants of vitamin D intake
  • 25-hydroxybitamin D assays and their clinical utility
  • Health disparities and vitamin D
  • Vitamin D deficiency in Canada
  • Vitamin D deficiency and its health consequences in Northern Europe
  • Vitamin D deficiency and consequences for the health of people in Mediterranean countries
  • Vitamin D deficiency in the Middle East and its health consequences
  • Vitamin D deficiency in the Middle East and its health consequences for adults
  • Vitamin D deficiency and its health consequences in Africa
  • Vitamin D deficiency and its health consequences in India
  • Vitamin D deficiency, rickets, and fluorosis in India
  • Vitamin D in Asia.
  • Vitamin D deficiency and its health consequences in New Zealand
  • Toxicity of vitamin D
  • Vitamin D deficiency in pregnancy and lactation and health consequences
  • Vitamin D deficiency in children and its health consequences
  • Dietary calcium deficiency and rickets
  • Vitamin D in fracture prevention and muscle function and fall prevention
  • Inherited defects of vitamin D metabolism
  • Molecular defects in the vitamin D receptor associated with hereditary 1,25-dihydroxyvitamin D resistant rickets (HVDRR)
  • Receptor-independent vitamin D resistance in subhuman and human primates
  • 25-hydroxyvitamin D-1x-hydroxylase: studies in mouse models and implications for human disease
  • The health benefits of solar irradiance and vitamin D and the consequences of their deprivation
  • Vitamin D status, solar radiation and cancer prognosis
  • The epidemiology of vitamin D and cancer risk
  • Vitamin D deficiency and the epidemiology of prostate cancer
  • Vitamin D for cancer prevention and survival
  • The anti-cancer effect of vitamin D: what do the randomized trials show?
  • Sunlight, skin cancer, and vitamin D
  • Vitamin D and the risk of type 1 diabetes
  • Vitamin D and multiple sclerosis
  • Vitamin D and type 2 diabetes
  • Role of vitamin D for cardiovascular health
  • Vitamin D, renin, and blood pressure
  • Role of vitamin D and vitamin D analogs for bone health and survival in chronic kidney disease
  • Role of vitamin D and ultraviolet radiation in chronic kidney disease
  • Role of vitamin D in rheumatoid arthritis
  • Vitamin D, respiratory infections, and obstructive airway diseases
  • Treatment of immunomediated diseases by vitamin D analogs
  • Clinical utility of 1,25-dihydroxyvitamin D3 and it analogues for the treatment of psoriasis
  • Affinity alkylating vitamin D analogs as molecular probes and therapeutic agents
  • Anti-inflammatory activity of calcitriol that contributes to its therapeutic and chemopreventive effects in prostate cancer.