Recombination and meiosis : models, means, and evolution /

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Bibliographic Details
Imprint:Berlin ; New York : Springer, c2008.
Description:1 online resource (xix, 390 p.) : ill.
Language:English
Series:Genome dynamics and stability, 1861-3373 ; 3
Genome Dynamics and Stability ; 3.
Subject:Genetic recombination.
Meiosis.
Recombination, Genetic.
Meiosis.
Models, Molecular.
Nondisjunction, Genetic.
Schizosaccharomyces -- genetics.
Science.
Natural history.
SCIENCE -- Life Sciences -- Molecular Biology.
Rekombination.
Genetik.
Meiose.
Genetic recombination.
Meiosis.
Electronic books.
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/8886230
Hidden Bibliographic Details
Other authors / contributors:Egel, Richard, 1942-
Lankenau, Dirk-Henner.
ISBN:9783540689843
3540689842
3540689834 (alk. paper)
9783540689836 (alk. paper)
Notes:Includes bibliographical references and index.
Description based on print version record.
Summary:Once per life cycle, mitotic nuclear divisions are replaced by meiosis I and II - reducing chromosome number from the diploid level to a haploid genome and recombining chromosome arms by crossing-over. In animals, all this happens during formation of eggs and sperm - in yeasts before spore formation. The mechanisms of reciprocal exchange at crossover/chiasma sites are central to mainstream meiosis. To initiate the meiotic exchange of DNA, surgical cuts are made as a form of calculated damage that subsequently is repaired by homologous recombination. These key events are accompanied by ancillar.
Other form:Print version: Recombination and meiosis. Berlin ; New York : Springer, c2008 9783540689836 3540689834
Standard no.:9786611861971
Description
Summary:

Once per life cycle, mitotic nuclear divisions are replaced by meiosis I and II - reducing chromosome number from the diploid level to a haploid genome and recombining chromosome arms by crossing-over. In animals, all this happens during formation of eggs and sperm - in yeasts before spore formation. The mechanisms of reciprocal exchange at crossover/chiasma sites are central to mainstream meiosis. To initiate the meiotic exchange of DNA, surgical cuts are made as a form of calculated damage that subsequently is repaired by homologous recombination. These key events are accompanied by ancillary provisions at the level of chromatin organization, sister chromatid cohesion and differential centromere connectivity. Great progress has been made in recent years in our understanding of these mechanisms. Questions still open primarily concern the placement of and mutual coordination between neighboring crossover events. Of overlapping significance, this book features two comprehensive treatises of enzymes involved in meiotic recombination, as well as the historical conceptualization of meiotic phenomena from genetical experiments. More specifically, these mechanisms are addressed in yeasts as unicellular model eukaryotes. Furthermore, evolutionary subjects related to meiosis are treated.

Physical Description:1 online resource (xix, 390 p.) : ill.
Bibliography:Includes bibliographical references and index.
ISBN:9783540689843
3540689842
3540689834 (alk. paper)
9783540689836 (alk. paper)
ISSN:1861-3373
;