Inhibitory regulation of excitatory neurotransmission /

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Bibliographic Details
Imprint:Berlin ; New York : Springer, c2008.
Description:1 online resource (xvi, 248 p.) : ill. (some col.)
Language:English
Series:Results and problems in cell differentiation ; 44
Results and problems in cell differentiation ; 44.
Subject:
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/8884536
Hidden Bibliographic Details
Other authors / contributors:Darlison, Mark G.
ISBN:9783540726029
3540726020
9783540726012 (alk. paper)
3540726012 (alk. paper)
6611352856
9786611352851
Notes:Includes bibliographical references and index.
Description based on print version record.
Summary:Within the central and peripheral nervous systems of animals, including man, inhibition is crucial to counterbalance excitatory neurotransmission, which is predominantly mediated by glutamate and its receptors. Although, particularly in brain, much of this inhibition is provided by classical post-synaptic GABAA receptors, many other proteins and mechanisms regulate excitation. These exist both to "fine tune" neurotransmission and to prevent overexcitation that could lead to conditions such as epilepsy and excitotoxicity, which can result in cell death. This book reviews aspects of GAB.
Other form:Print version: Inhibitory regulation of excitatory neurotransmission. Berlin ; New York : Springer, c2008 9783540726012 3540726012