Statistics applied to clinical studies /
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| Author / Creator: | Cleophas, Ton J. M. |
|---|---|
| Edition: | 5th ed. |
| Imprint: | Dordrecht ; New York : Springer, c2012. |
| Description: | 1 online resource (xxxv, 743 p.) |
| Language: | English |
| Subject: | |
| Format: | E-Resource Book |
| URL for this record: | http://pi.lib.uchicago.edu/1001/cat/bib/8872901 |
Table of Contents:
- Hypotheses, Data, Stratification
- The Analysis of Efficacy Data
- The Analysis of Safety Data
- Log Likelihood Ratio Tests for Safety Data Analysis
- Equivalence Testing
- Statistical Power and Sample Size
- Interim Analyses
- Controlling the Risk of False Positive Clinical Trials
- Multiple Statistical Inferences
- The Interpretation of the p-Values
- Research Data Closer to Expectation than Compatible with Random Sampling
- Statistical Tables for Testing Data Closer to Expectation than Compatible with Random Sampling
- Data Dispersion Issues
- Linear Regression, Basic Approach
- Linear Regression for Assessing Precision, Confounding, Interaction, Basic Approach
- Curvilinear Regression
- Logistic and Cox Regression, Markov Models, Laplace Transformations
- Regression Modeling for Improved Precision
- Post-hoc Analyses in Clinical Trials, A Case for Logistic Regression Analysis
- Multistage Regression
- Categorical Data
- Missing Data
- Poisson Regression
- More on Non Linear Relationships, Splines
- Multivariate Analysis
- Bhattacharya Modeling
- Trend-Testing
- Confounding
- Propensity Score Matching
- Interaction
- Time-Dependent Factor Analysis
- Meta-analysis, Basic Approach
- Meta-analysis, Review and Update of Methodologies
- Meta-regression
- Crossover Studies with Continuous Variables
- Crossover Studies with Binary Responses
- Cross-Over Trials Should Not Be Used to Test Treatments with Different Chemical Class
- Quality-Of-Life Assessments in Clinical Trials
- Item Response Modeling
- Statistical Analysis of Genetic Data
- Relationship Among Statistical Distributions
- Testing Clinical Trials for Randomness
- Clinical Trials Do Not Use Random Samples Anymore
- Clinical Data Where Variability Is More Important Than Averages
- Testing Reproducibility
- Validating Qualitative Diagnostic Tests
- Uncertainty of Qualitative Diagnostic Tests
- Meta-Analysis of Qualitative Diagnostic Tests
- c-Statistic Versus Logistic Regression for Assessing the Performance of Qualitative Diagnostic Accuracy
- Validating Quantitative Diagnostic Tests
- Summary of Validation Procedures for Diagnostic Tests
- Validating Surrogate Endpoints of Clinical Trials
- Binary Partitioning
- Methods for Repeated Measures Analysis
- Mixed Linear Models for Repeated Measures
- Advanced Analysis of Variance, Random Effects and Mixed Effects Models
- Monte Carlo Methods for Data Analysis
- Artificial Intelligence
- Fuzzy Logic
- Physicians' Daily Life and the Scientific Method
- Incident Analysis and the Scientific Method
- Clinical Trials: Superiority-Testing
- Noninferiority Testing
- Time Series
- Odds Ratios and Multiple Regression Models, Why and How to Use Them
- Statistics Is No "Bloodless" Algebra
- Bias Due to Conflicts of Interests, Some Guidelines.