Gene therapy of cancer : methods and protocols /

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Bibliographic Details
Edition:2nd ed.
Imprint:New York, NY : Humana, c2009.
Description:1 online resource (xiv, 731 p., [8] p. of plates) : ill. (some col.)
Language:English
Series:Springer protocols
Methods in molecular biology, 1064-3745 ; 542
Methods in molecular biology (Clifton, N.J.) ; v. 542.
Springer protocols.
Subject:Cancer -- Gene therapy -- Laboratory manuals.
Neoplasms -- therapy.
Gene Therapy -- methods.
Cancer -- Thérapie génique.
Cancer -- Gene therapy.
Electronic books.
Laboratory manuals.
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/8870263
Hidden Bibliographic Details
Other authors / contributors:Walther, Wolfgang.
Stein, Ulrike.
ISBN:9781597455619
159745561X
Notes:Includes bibliographical references and index.
Description based on print version record.
Other form:Print version: Gene therapy of cancer. 2nd ed. New York, NY : Humana, c2009 1934115851 9781934115855
Table of Contents:
  • Section 1. Experimental approaches in cancer therapy
  • 1. Development of gene therapy / Jean-Pierre Gillet ... [et al.]
  • Subsection B
  • Vectorology for cancer gene therapy
  • 2. Designing adenoviral vectors for tumor-specific targeting / Ramon Alemany
  • 3. Analysis of HSV oncolytic virotherapy in organotypic cultures / Giulia Fulci, Brent Passer
  • 4. Use of minicircle plasmids for gene therapy / Peter Mayrhofer, Martin Schleef, Wolfgang Jechlinger
  • 5. Transposable elements as plasmid-based vectors for long-term gene transfer into tumors / John R. Ohlfest, Zoltán Ivics, Zsuzsanna Izsvák
  • 6. Designing plasmid vectors / Oleg Tolmachov
  • 7. Development of bacterial vectors for tumor-targeted gene therapy / Li-Jun Jia and Zi-Chun Hua
  • Subsection C Nonviral transfer technologies in cancer gene therapy
  • 8. Electroporative gene transfer / Marco Schmeer
  • 9. Gene gun delivery systems for cancer vaccine approaches / Kandan Aravindaram and Ning Sun Yang
  • 10. Ultrasound-mediated gene transfection / Loreto B. Feril Jr.
  • 11. Nonviral jet-injection technology for intratumoral in vivo gene transfer of naked DNA / Wolfgang Walther ... [et al.]
  • Subsection D: Experimental studies in cancer gene therapy
  • 12. Methods for constructing and evaluating antitumor DNA vaccines / Brian M. Olson and Douglas G. McNeel
  • 13. Immunity of lentiviral vector-modified dendritic cells / Shuhong Han and Lung-Ji Chang
  • 14. Saporin suicide gene therapy / Natasa Zarovni, Riccardo Vago, and Maria Serena Fabbrini
  • 15. Using in vivo biopanning for the development of radiation-guided drug delivery systems / Jerry J. Jaboin, Zhaozhong Han, and Dennis E. Hallahan
  • 16. Chemosensitization of Tumor Cells: Inactivation of nuclear factor-kappa B associated with chemosensitivity in melanoma cells after combination treatment with E2F-1 and doxorubicin / Hongying Hao, H. Sam Zhou, and Kelly M. McMasters
  • 17. Induction of tumor cell apoptosis by TRAIL gene therapy / Thomas S. Griffith
  • 18. Silencing epidermal growth factor receptor by RNA interference in glioma / Chunsheng Kang, Peiyu Pu, and Hao Jiang
  • 19. Delivery of phosphorodiamidate morpholino antisense oligomers in cancer cells / Gayathri R. Devi
  • 20. Use of RNA aptamers for the modulation of cancer cell signaling / Sunjoo Jeong, Hee Kyu Lee, and Mee Young Kim
  • 21. G-rich oligonucleotides for cancer treatment / Paula J. Bates, Enid W. Choi, and Lalitha V. Nayak.
  • Section 2. Clinical approaches in cancer gene therapy
  • Subsection A. Requirements for clinical gene therapy trials
  • 22. Regulatory aspects for translating gene therapy research into the clinic / Carolyn M. Laurencot and Sheryl Ruppel
  • 23. Ethics of cancer gene transfer clinical research / Jonathan Kimmelman
  • 24. Virus production for clinical gene therapy / Tiago Vicente ... [et al.]
  • 25. Production of plasmid DNA as pharmaceutical / Martin Schleef and Markus Blaesen
  • Subsection B. Clinical protocols in cancer gene therapy
  • 26. Gene immunotherapy for non-small cell lung cancer / John J. Nemunaitis
  • 27. Gene therapy for antitumor vaccination / Seunghee Kim-Schulze and Howard L. Kaufman
  • 28. HSV-tk/IL-2 gene therapy for glioblastoma multiforme / Luisa Barzon ... [et al.]
  • 29. Construction and characterization of an oncolytic HSV vector containing a fusogenic glycoprotein and prodrug activation for enhanced local tumor control / Guy R. Simpson and Robert S. Coffin
  • 30. Newcastle disease virus: a promising vector for viral therapy, immune therapy, and gene therapy of cancer / Volker Schirrmacher and Philippe Fournier
  • 31. Oncolytic viral therapy using reovirus / Chandini Thirukkumaran and Don G. Morris
  • 32. Design and testing of novel oncolytic vaccinia strains / Steve H. Thorne
  • 33. Tumor-targeted salmonella typhimurium overexpressing cytosine deaminase: a novel, tumor-selective therapy / Ivan King, Martina Itterson, and David Bermudes
  • 34. Chemoprotection by transfer of resistance genes / Tulin Budak-Alpdogan and Joseph R. Bertino
  • 35. Phase I clinical trial of locoregional administration of the oncolytic adenovirus ONYX-015 in combination with mitomycin-C, doxorubicin, and cisplatin chemotherapy in patients with advanced sarcomas / Mateusz Opyrchal, Ileana Aderca, and Evanthia Galanis.