Gene therapy of cancer : methods and protocols /
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Edition: | 2nd ed. |
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Imprint: | New York, NY : Humana, c2009. |
Description: | 1 online resource (xiv, 731 p., [8] p. of plates) : ill. (some col.) |
Language: | English |
Series: | Springer protocols Methods in molecular biology, 1064-3745 ; 542 Methods in molecular biology (Clifton, N.J.) ; v. 542. Springer protocols. |
Subject: | Cancer -- Gene therapy -- Laboratory manuals. Neoplasms -- therapy. Gene Therapy -- methods. Cancer -- Thérapie génique. Cancer -- Gene therapy. Electronic books. Laboratory manuals. |
Format: | E-Resource Book |
URL for this record: | http://pi.lib.uchicago.edu/1001/cat/bib/8870263 |
Table of Contents:
- Section 1. Experimental approaches in cancer therapy
- 1. Development of gene therapy / Jean-Pierre Gillet ... [et al.]
- Subsection B
- Vectorology for cancer gene therapy
- 2. Designing adenoviral vectors for tumor-specific targeting / Ramon Alemany
- 3. Analysis of HSV oncolytic virotherapy in organotypic cultures / Giulia Fulci, Brent Passer
- 4. Use of minicircle plasmids for gene therapy / Peter Mayrhofer, Martin Schleef, Wolfgang Jechlinger
- 5. Transposable elements as plasmid-based vectors for long-term gene transfer into tumors / John R. Ohlfest, Zoltán Ivics, Zsuzsanna Izsvák
- 6. Designing plasmid vectors / Oleg Tolmachov
- 7. Development of bacterial vectors for tumor-targeted gene therapy / Li-Jun Jia and Zi-Chun Hua
- Subsection C Nonviral transfer technologies in cancer gene therapy
- 8. Electroporative gene transfer / Marco Schmeer
- 9. Gene gun delivery systems for cancer vaccine approaches / Kandan Aravindaram and Ning Sun Yang
- 10. Ultrasound-mediated gene transfection / Loreto B. Feril Jr.
- 11. Nonviral jet-injection technology for intratumoral in vivo gene transfer of naked DNA / Wolfgang Walther ... [et al.]
- Subsection D: Experimental studies in cancer gene therapy
- 12. Methods for constructing and evaluating antitumor DNA vaccines / Brian M. Olson and Douglas G. McNeel
- 13. Immunity of lentiviral vector-modified dendritic cells / Shuhong Han and Lung-Ji Chang
- 14. Saporin suicide gene therapy / Natasa Zarovni, Riccardo Vago, and Maria Serena Fabbrini
- 15. Using in vivo biopanning for the development of radiation-guided drug delivery systems / Jerry J. Jaboin, Zhaozhong Han, and Dennis E. Hallahan
- 16. Chemosensitization of Tumor Cells: Inactivation of nuclear factor-kappa B associated with chemosensitivity in melanoma cells after combination treatment with E2F-1 and doxorubicin / Hongying Hao, H. Sam Zhou, and Kelly M. McMasters
- 17. Induction of tumor cell apoptosis by TRAIL gene therapy / Thomas S. Griffith
- 18. Silencing epidermal growth factor receptor by RNA interference in glioma / Chunsheng Kang, Peiyu Pu, and Hao Jiang
- 19. Delivery of phosphorodiamidate morpholino antisense oligomers in cancer cells / Gayathri R. Devi
- 20. Use of RNA aptamers for the modulation of cancer cell signaling / Sunjoo Jeong, Hee Kyu Lee, and Mee Young Kim
- 21. G-rich oligonucleotides for cancer treatment / Paula J. Bates, Enid W. Choi, and Lalitha V. Nayak.
- Section 2. Clinical approaches in cancer gene therapy
- Subsection A. Requirements for clinical gene therapy trials
- 22. Regulatory aspects for translating gene therapy research into the clinic / Carolyn M. Laurencot and Sheryl Ruppel
- 23. Ethics of cancer gene transfer clinical research / Jonathan Kimmelman
- 24. Virus production for clinical gene therapy / Tiago Vicente ... [et al.]
- 25. Production of plasmid DNA as pharmaceutical / Martin Schleef and Markus Blaesen
- Subsection B. Clinical protocols in cancer gene therapy
- 26. Gene immunotherapy for non-small cell lung cancer / John J. Nemunaitis
- 27. Gene therapy for antitumor vaccination / Seunghee Kim-Schulze and Howard L. Kaufman
- 28. HSV-tk/IL-2 gene therapy for glioblastoma multiforme / Luisa Barzon ... [et al.]
- 29. Construction and characterization of an oncolytic HSV vector containing a fusogenic glycoprotein and prodrug activation for enhanced local tumor control / Guy R. Simpson and Robert S. Coffin
- 30. Newcastle disease virus: a promising vector for viral therapy, immune therapy, and gene therapy of cancer / Volker Schirrmacher and Philippe Fournier
- 31. Oncolytic viral therapy using reovirus / Chandini Thirukkumaran and Don G. Morris
- 32. Design and testing of novel oncolytic vaccinia strains / Steve H. Thorne
- 33. Tumor-targeted salmonella typhimurium overexpressing cytosine deaminase: a novel, tumor-selective therapy / Ivan King, Martina Itterson, and David Bermudes
- 34. Chemoprotection by transfer of resistance genes / Tulin Budak-Alpdogan and Joseph R. Bertino
- 35. Phase I clinical trial of locoregional administration of the oncolytic adenovirus ONYX-015 in combination with mitomycin-C, doxorubicin, and cisplatin chemotherapy in patients with advanced sarcomas / Mateusz Opyrchal, Ileana Aderca, and Evanthia Galanis.