Gene therapy of cancer : methods and protocols /

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Bibliographic Details
Edition:2nd ed.
Imprint:New York, NY : Humana, c2009.
Description:xiv, 731 p., [8] p. of plates : ill. (some col.) ; 27 cm.
Language:English
Series:Methods in molecular biology, 1064-3745 ; 542
Methods in molecular biology (Clifton, N.J.) ; v. 542.
Subject:
Format: Print Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/7714661
Hidden Bibliographic Details
Other authors / contributors:Walther, Wolfgang.
Stein, Ulrike.
ISBN:1934115851
9781934115855
9781597455619 (e-ISBN)
159745561X (e-ISBN)
Notes:"Springer protocols"--cover.
Includes bibliographical references and index.

MARC

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505 0 |a Section 1. Experimental approaches in cancer therapy -- 1. Development of gene therapy / Jean-Pierre Gillet, ... [et al.] -- Subsection B -- Vectorology for cancer gene therapy -- 2. Designing adenoviral vectors for tumor-specific targeting / Ramon Alemany -- 3. Analysis of HSV oncolytic virotherapy in organotypic cultures / Giulia Fulci, Brent Passer -- 4. Use of minicircle plasmids for gene therapy / Peter Mayrhofer, Martin Schleef, Wolfgang Jechlinger -- 5. Transposable elements as plasmid-based vectors for long-term gene transfer into tumors / John R. Ohlfest, Zoltán Ivics, Zsuzsanna Izsvák -- 6. Designing plasmid vectors / Oleg Tolmachov -- 7. Development of bacterial vectors for tumor-targeted gene therapy / Li-Jun Jia and Zi-Chun Hua -- Subsection C Nonviral transfer technologies in cancer gene therapy -- 8. Electroporative gene transfer / Marco Schmeer -- 9. Gene gun delivery systems for cancer vaccine approaches / Kandan Aravindaram and Ning Sun Yang -- 10. Ultrasound-mediated gene transfection / Loreto B. Feril Jr. -- 11. Nonviral jet-injection technology for intratumoral in vivo gene transfer of naked DNA / Wolfgang Walther ... [et al.] -- Subsection D: Experimental studies in cancer gene therapy -- 12. Methods for constructing and evaluating antitumor DNA vaccines / Brian M. Olson and Douglas G. McNeel -- 13. Immunity of lentiviral vector-modified dendritic cells / Shuhong Han and Lung-Ji Chang -- 14. Saporin suicide gene therapy / Natasa Zarovni, Riccardo Vago, and Maria Serena Fabbrini -- 15. Using in vivo biopanning for the development of radiation-guided drug delivery systems / Jerry J. Jaboin, Zhaozhong Han, and Dennis E. Hallahan -- 16. Chemosensitization of Tumor Cells: Inactivation of nuclear factor-kappa B associated with chemosensitivity in melanoma cells after combination treatment with E2F-1 and doxorubicin / Hongying Hao, H. Sam Zhou, and Kelly M. McMasters -- 17. Induction of tumor cell apoptosis by TRAIL gene therapy / Thomas S. Griffith -- 18. Silencing epidermal growth factor receptor by RNA interference in glioma / Chunsheng Kang, Peiyu Pu, and Hao Jiang -- 19. Delivery of phosphorodiamidate morpholino antisense oligomers in cancer cells / Gayathri R. Devi -- 20. Use of RNA aptamers for the modulation of cancer cell signaling / Sunjoo Jeong, Hee Kyu Lee, and Mee Young Kim -- 21. G-rich oligonucleotides for cancer treatment / Paula J. Bates, Enid W. Choi, and Lalitha V. Nayak -- 
505 0 |a Section 2. Clinical approaches in cancer gene therapy -- Subsection A. Requirements for clinical gene therapy trials -- 22. Regulatory aspects for translating gene therapy research into the clinic / Carolyn M. Laurencot and Sheryl Ruppel -- 23. Ethics of cancer gene transfer clinical research / Jonathan Kimmelman -- 24. Virus production for clinical gene therapy / Tiago Vicente, ... [et al.] -- 25. Production of plasmid DNA as pharmaceutical / Martin Schleef and Markus Blaesen --Subsection B. Clinical protocols in cancer gene therapy -- 26. Gene immunotherapy for non-small cell lung cancer / John J. Nemunaitis -- 27. Gene therapy for antitumor vaccination / Seunghee Kim-Schulze and Howard L. Kaufman -- 28. HSV-tk/IL-2 gene therapy for glioblastoma multiforme / Luisa Barzon, ... [et al.] -- 29. Construction and characterization of an oncolytic HSV vector containing a fusogenic glycoprotein and prodrug activation for enhanced local tumor control / Guy R. Simpson and Robert S. Coffin -- 30. Newcastle disease virus: a promising vector for viral therapy, immune therapy, and gene therapy of cancer / Volker Schirrmacher and Philippe Fournier -- 31. Oncolytic viral therapy using reovirus / Chandini Thirukkumaran and Don G. Morris -- 32. Design and testing of novel oncolytic vaccinia strains / Steve H. Thorne -- 33. Tumor-targeted salmonella typhimurium overexpressing cytosine deaminase: a novel, tumor-selective therapy / Ivan King, Martina Itterson, and David Bermudes -- 34. Chemoprotection by transfer of resistance genes / Tulin Budak-Alpdogan and Joseph R. Bertino -- 35. Phase I clinical trial of locoregional administration of the oncolytic adenovirus ONYX-015 in combination with mitomycin-C, doxorubicin, and cisplatin chemotherapy in patients with advanced sarcomas / Mateusz Opyrchal, Ileana Aderca, and Evanthia Galanis. 
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