Statistical monitoring of clinical trials : a unified approach /

Statistical monitoring of clinical trials : a unified approach /

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Bibliographic Details
Author / Creator:	Proschan, Michael A.
Imprint:	New York, NY : Springer, c2006.
Description:	xiii, 258 p. : ill. ; 24 cm.
Language:	English
Series:	Statistics for biology and health
Subject:	Clinical trials -- Statistical methods. Drugs -- Testing. Clinical Trials -- statistics & numerical data. Statistics as Topic. Bayes Theorem. Data Interpretation, Statistical. Clinical trials -- Statistical methods. Drugs -- Testing.
Format:	Print Book
URL for this record:	http://pi.lib.uchicago.edu/1001/cat/bib/6201654

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Other authors / contributors:	Lan, K. K. Gordan. Wittes, Janet Turk.
ISBN:	0387300597
Notes:	Includes bibliographical references (p. [247]-254) and index.
Standard no.:	9780387300597

Table of Contents:

Introduction
A general framework
Power: conditional, unconditional, and predictive
Historical monitoring boundaries
Spending functions
Practical survival monitoring
Inference following a group-sequential trial
Options when Brownian motion does not hold
Monitoring for safety
Bayesian monitoring
Adaptive sample size methods
Topics not covered