Statistics applied to clinical trials /
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| Author / Creator: | Cleophas, Ton J. M. |
|---|---|
| Edition: | 3rd ed. |
| Imprint: | Dordrecht, the Netherlands : Springer, c2006. |
| Description: | xiv, 366 p. : ill. ; 25 cm. |
| Language: | English |
| Subject: | |
| Format: | Print Book |
| URL for this record: | http://pi.lib.uchicago.edu/1001/cat/bib/5922274 |
Table of Contents:
- Ch. 1. Hypotheses, data, stratification
- Ch. 2. The analysis of efficacy data of drug trials
- Ch. 3. The analysis of safety data of drug trials
- Ch. 4. Equivalence testing
- Ch. 5. Statistical power and sample size
- Ch. 6. Interim analyses
- Ch. 7. Multiple statistical inferences
- Ch. 8. Controlling the risk of false positive clinical trials
- Ch. 9. The interpretation of the p-values
- Ch. 10. Research data closer to expectation than compatible with random sampling
- Ch. 11. Principles of linear regression
- Ch. 12. Subgroup analysis using multiple linear regression : confounding, interaction, synergism
- Ch. 13. Curvilinear regression
- Ch. 14. Logistic and cox regression, problems with regression modeling, Markow models
- Ch. 15. Regression modeling for improved precision
- Ch. 16. Post-HOC analysis in clinical trials, a case for logistic regression analysis
- Ch. 17. Interaction effects in clinical trials
- Ch. 18. Meta-analysis
- Ch. 19. Crossover studies with continuous variables : power analysis
- Ch. 20. Crossover studies with binary responses
- Ch. 21. Cross-over trials should not be used to test treatments with different chemical class
- Ch. 22. Quality-of-life assessments in clinical trials
- Ch. 23. Statistical analysis of genetic data
- Ch. 24. Relationship among statistical distributions
- Ch. 25. Testing clinical trials for randomness
- Ch. 26. Clinical data where variability is more important than averages
- Ch. 27. Testing reproducibility
- Ch. 28. Accuracy of diagnostic tests
- Ch. 29. Advanced analysis of variance
- Ch. 30. Statistics is no "bloodless" algebra
- Ch. 31. Bias due to conflicts of interests, some guidelines.
