Antiepileptic drugs /

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Bibliographic Details
Edition:5th ed.
Imprint:Philadelphia : Lippincott Williams & Wilkins, c2002.
Description:xv, 968 p. : ill. ; 29 cm.
Language:English
Subject:Epilepsy -- Chemotherapy.
Anticonvulsants.
Anticonvulsants -- therapeutic use.
Anticonvulsants -- pharmacology.
Epilepsy -- drug therapy.
Anticonvulsants.
Epilepsy -- Chemotherapy.
Format: Print Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/4746692
Hidden Bibliographic Details
Other authors / contributors:Levy, ReneĢ H.
ISBN:0781723213
Notes:Includes bibliographical references and index.
Table of Contents:
  • Contributing Authors
  • Preface
  • Section I.. General Principles
  • 1. Principles of Antiepileptic Drug Action
  • 2. Neurophysiological Effects of Antiepileptic Drugs
  • 3. Discovery and Preclinical Development of Antiepileptic Drugs
  • 4. New Antiepileptic Drug Development: Medical Perspective
  • 5. Clinical Development of Antiepileptic Drugs: Industry Perspective
  • 6. The Development of Antiepilepsy Drugs: Regulatory Perspective
  • 7. Antiepileptic Drug Monotherapy in Adults: Selection and Use in New-Onset Epilepsy
  • 8. Combination Therapy and Drug Interactions
  • 9. Laboratory Monitoring of Antiepileptic Drugs
  • 10. Safety Monitoring of Antiepileptic Drugs
  • 11. Use of Antiepileptic Drugs in Children
  • 12. Antiepileptic Drug Use in Women
  • 13. Epilepsy in the Elderly
  • 14. Treatment of Status Epilepticus
  • 15. Prevention of Epileptogenesis
  • Section II.. Benzodiazepines
  • 20. Mechanisms of Action
  • 16. Mechanisms of Action
  • 17. Chemistry, Biotransformation, and Pharmacokinetics
  • 18. Clinical Efficacy and Use in Epilepsy
  • 19. Adverse Effects
  • Section III.. Carbamazepine
  • 21. Chemistry, Biotransformation, and Pharmacokinetics
  • 22. Interactions with Other Drugs
  • 23. Clinical Efficacy and Use in Epilepsy
  • 24. Clinical Efficacy and Use in Other Neurological Disorders
  • 25. Clinical Efficacy and Use in Psychiatric Disorders
  • 26. Adverse Effects
  • Section IV.. Felbamate
  • 27. Felbamate
  • Section V.. Gabapentin
  • 28. Mechanisms of Action
  • 29. Chemistry, Biotransformation, Pharmacokinetics, and Interactions
  • 30. Clinical Use
  • 31. Clinical Efficacy and Use in Other Neurological Disorders
  • 32. Clinical Efficacy and Use in Psychiatric Disorders
  • 33. Adverse Effects
  • Section VI.. Lamotrigine
  • 34. Mechanisms of Action
  • 35. Chemistry, Biotransformation, and Pharmacokinetics
  • 36. Interactions with Other Drugs
  • 37. Clinical Efficacy and Use in Epilepsy
  • 38. Efficacy and Use in Nonepileptic Disorders
  • 39. Adverse Effects
  • Section VII.. Levetiracetam
  • 40. Mechanisms of Action
  • 41. Chemistry, Biotransformation, Pharmacokinetics, and Drug Interactions
  • 42. Clinical Use
  • 43. Adverse Experiences
  • Section VIII.. Oxcarbazepine
  • 44. Mechanisms of Action
  • 45. Chemistry, Biotransformation, and Pharmacokinetics
  • 46. Interactions with Other Drugs
  • 47. Clinical Efficacy and Use in Epilepsy
  • 48. Clinical Efficacy and Use in Psychiatric Disorders
  • 49. Adverse Effects
  • Section IX.. Phenobarbital and Other Barbiturates
  • 50. Mechanisms of Action
  • 51. Chemistry, Biotransformation, and Pharmacokinetics
  • 52. Interactions with Other Drugs
  • 53. Clinical Efficacy and Use in Epilepsy
  • 54. Clinical Efficacy and Use in Nonepileptic Disorders
  • 55. Adverse Effects
  • 56. Methylphenobarbital
  • Section X.. Phenytoin and other Hydantoins
  • 57. Mechanisms of Action
  • 58. Chemistry and Biotransformation
  • 59. Interactions with Other Drugs
  • Section XI.. Primidone
  • 60. Clinical Efficacy and Use in Epilepsy
  • 61. Clinical Efficacy and Use in Other Neurological Disorders
  • 62. Clinical Efficacy and Use in Psychiatric Disorders
  • 63. Adverse Effects
  • 64. Fosphenytoin
  • 65. Primidone
  • Section XII.. Succinimides
  • 66. Mechanisms of Action
  • 67. Ethosuximide: Chemistry, Biotransformation, Pharmacokinetics, and Drug Interactions
  • 68. Clinical Efficacy and Use in Epilepsy
  • 69. Adverse Effects
  • 70. Methsuximide
  • Section XIII.. Tiagabine
  • 71. Mechanisms of Action
  • 72. Chemistry, Biotransformation, and Pharmacokinetics
  • 73. Drug Interactions
  • 74. Clinical Efficacy and Use in Epilepsy
  • 75. Clinical Efficacy and Use in Nonepileptic Disorders
  • 76. Adverse Effects
  • Section XIV.. Topiramate
  • 77. Mechanisms of Action
  • 78. Chemistry, Biotransformation, and Pharmacokinetics
  • 79. Drug Interactions
  • 80. Clinical Efficacy and Use in Epilepsy
  • 81. Clinical Efficacy and Use in Nonepileptic Disorders
  • 82. Adverse Effects
  • 85. Drug Interactions
  • Section XV.. Valproic Acid
  • 83. Mechanisms of Action
  • 84. Chemistry, Biotransformation, and Pharmacokinetics
  • 86. Clinical Efficacy and Use in Epilepsy
  • 87. Clinical Efficacy and Use in Other Neurological Disorders
  • 88. Clinical Efficacy and Use in Psychiatric Disorders
  • 89. Adverse Effects
  • Section XVI.. Vigabatrin
  • 90. Vigabatrin
  • Section XVII.. Zonisamide
  • 91. Mechanisms of Action
  • 92. Chemistry, Biotransformation, and Pharmacokinetics
  • 93. Drug Interactions
  • 94. Clinical Efficacy and Use in Epilepsy
  • 95. Adverse Effects
  • Section XVIII.. Drugs in Development
  • 96. Pregabalin
  • 97. Rufinamide
  • Subject Index
  • 98. Drugs in Early Clinical Development