Intermolecular cross-talk in tumor metastasis /
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Imprint: | Amsterdam ; Washington, DC : IOS Press, c1999. |
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Description: | viii, 309 p. : ill. ; 25 cm. |
Language: | English |
Series: | NATO science series. Series A, Life sciences, 1387-6686 ; vol. 311 |
Subject: | |
Format: | Print Book |
URL for this record: | http://pi.lib.uchicago.edu/1001/cat/bib/4625386 |
Summary: | Metastasis of tumours is a sequence of events taking place after the appearance of a primary tumour. The potency of a tumour to metastasise greatly depends on the molecular interactions between tumour components (cellular differentiation and heterogeneity, surface antigenic determinants etc.) and the micro-environment. The complexity and diversity in the composition of tissue micro-environment is in great extent determining the metastatic behaviour or a primary tumour. Extracellular matrix composition, rearrangement of cytoskeleton, cell antigenicity , expression of metastasis-related novel genes, cell adhesion and novel therapeutical approaches such as blockage of angiogenesis, are the major topics discussed in detail in this volume. |
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Item Description: | "Published in cooperation with NATO Scientific Affairs Division." "Proceedings of the NATO Advanced Study Institute on Intermolecular Cross-Talk in Tumor Metastasis, Athens, Greece, 24 July-3 August 1998"--T.p. verso. |
Physical Description: | viii, 309 p. : ill. ; 25 cm. |
Bibliography: | Includes bibliographical references and index. |
ISBN: | 9051994567 (IOS Press) 4274902897 (Ohmsha) |