Growth factors and tumor promotion : implications for risk assessment : proceedings of the Seventh International Conference on Carcinogenesis and Risk Assessment, held in Austin, Texas, on December 1-4,1993 /

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Bibliographic Details
Meeting name:International Conference on Carcinogenesis and Risk Assessment (7th : 1993 : Austin, Tex.)
Imprint:New York : Wiley-Liss, c1995.
Description:xix, 470 p. ; 24 cm.
Language:English
Series:Progress in clinical and biological research ; 391
Progress in clinical and biological research. ; v. 391.
Subject:
Format: Print Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/2348626
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Other authors / contributors:McClain, Michael.
ISBN:0471121452 (alk. paper)
Notes:Includes bibliographical references and index.
Table of Contents:
  • Preface / R. Michael McClain, Thomas J. Slaga, Robert LeBoeuf and Henry Pitot
  • Skin Carcinogenesis: Characteristics, Mechanisms, and Prevention / Thomas J. Slaga, John DiGiovanni, Lloyd D. Winberg and Irina V. Budunova
  • The Instability of Tumor Promotion in Relation to Human Cancer Risk / Henry C. Pitot and Yvonne P. Dragan
  • The Role of Growth Factors in Mouse Skin Tumor Promotion and Premalignant Progression / Stuart H. Yuspa, Henry Hennings, Andrezj Dlugosz, Tamar Tennenbaum and Adam Glick
  • A Decision Tree Approach for Carcinogen Risk Assessment / Byron E. Butterworth and Sandra R. Eldridge
  • Modulation of Gap Junctional Intercellular Communication in Rodent, Monkey, and Human Hepatocyte by Nongenotoxic Compounds / Thomas K. Baker, Stephen Bachowski, Donald E. Stevenson, Earl F. Walborg, Jr. and James E. Klaunig
  • Hypomethylation of DNA: A Possible Epigenetic Mechanism Involved in Tumor Promotion / Jennifer L. Counts and Jay I. Goodman
  • Role of Reactive Intermediates in Tumor Promotion and Progression / Thomas Kensler, Kathryn Guyton, Patricia Egner, Timothy McCarthy, Steven Lesko and Steven Akman
  • The Tumor Promoter Receptor Protein Kinase C: A Novel Target for Chemoprevention and Therapy of Human Colon Cancer / Catherine A. O'Brian, Nancy E. Ward, Karen R. Gravitt and Krishna P. Gupta
  • Calcium, Cell Death, and Tumor Promotion / Benjamin F. Trump and Irene K. Berezesky
  • Transforming Growth Factor-[beta]s in Mammary Tumorigenesis: Promoters or Antipromoters? / Lalage M. Wakefield, John J. Letterio, Andrew G. Geiser, Kathleen C. Flanders, Joyce O'Shaughnessy, Anita B. Roberts and Michael B. Sporn
  • Liver Tumor Promotion: A Process of Natural Selection / Randy L. Jirtle
  • The Pro-Inflammatory and Hyperplasiogenic Action of Interleukin-1[alpha] in Mouse Skin / Susan M. Fischer, Wha Young Lee and Mary F. Locniskar
  • HGF in Liver Regeneration and Tumor Promotion / George K. Michalopoulos
  • Hormonal and Genetic Interactions in Murine Hepatocarcinogenesis / Therese M. Poole and Norman R. Drinkwater
  • Genetic Factors Controlling Responsiveness to Skin Tumor Promotion in Mice / John DiGiovanni
  • Hepatocarcinogenesis in Transgenic Mice / Eric P. Sandgren and Glenn Merlino
  • A Transgenic Mouse Model (TG.AC) for Skin Carcinogenesis: Inducible Transgene Expression as a Second Critical Event / Laura A. Hansen, Judson W. Spalding, John E. French and Raymond W. Tennant
  • Saccharin-Induced Bladder Cancer in Rats / Emily M. Garland and Samuel M. Cohen
  • Benzoyl Peroxide: Review of Experimental Carcinogenesis and Human Safety Data / Robert L. Binder, Marilyn J. Aardema and Edward D. Thompson
  • Peroxisome Proliferators: Potential Role of Altered Hepatocyte Growth and Differentiation in Tumor Development / Russell C. Cattley, Richard T. Miller and J. Christopher Corton
  • Considerations Concerning the Murine Hepatocarcinogenicity of Selected Chlorinated Hydrocarbons / R. R. Maronpot, C. H. Anna, T. R. Devereux, G. W. Lucier, B. E. Butterworth and M. W. Anderson
  • Phenobarbital Mouse Liver Tumors: Implications of Hepatic Tumor Promotion for Cancer Risk Assessment / R. Michael McClain
  • The Species Specificity of Dieldrin- or Phenobarbital-Induced Hepatocarcinogenesis: Case Studies With Implications for Human Health Risk Assessment / Donald E. Stevenson, Earl F. Walborg, Jr. and James E. Klaunig
  • The Use of Biological Data in Addition to the Carcinogen Bioassay in Quantitative Risk Assessment / Robert J. Scheuplein
  • Risk Assessment for Carcinogenesis Promoting Agents: Need for a Weight of All the Evidence Approach / David B. Clayson
  • Mechanistic Considerations in Risk Assessment for Epigenetic Tumor-Promoting Carcinogens / Guy M. Williams and John Whysner
  • The Potential Role of Oxidative Stress in Nongenotoxic Carcinogenesis in the Mouse Liver / Steven Bachowski, Yong Xu, Thomas K. Baker, Donald E. Stevenson, Earl F. Walborg, Jr. and James E. Klaunig
  • Hepatic Effects of Dieldrin and Phenobarbital in Male B6C3F[subscript 1] Mice and Fisher 344 Rats: Species Selective Induction of DNA Synthesis / Kyle L. Kolaja, Donald E. Stevenson, Jason T. Johnson, Earl F. Walborg, Jr. and James E. Klaunig
  • The Effect of Dieldrin and Phenobarbital on Prenoplastic Hepatic Lesion Growth in Male F344 Rat and B6CF[subscript 1] Mouse / Kyle L. Kolaja, Donald E. Stevenson, Earl F. Walborg, Jr. and James E. Klaunig
  • Modulation of Gap Junctional Intercellular Communication by Phosphorylation: Effects of Growth Factors, Kinase Activators, and Phosphatase Inhibitors / Svein-Ole Mikalsen, Trine Husoy and Tore Sanner
  • Induction of Short-Term Biomarkets of Tumor Promotion in Skin of CD-1 Mice by Petroleum Middle Distillates: Preliminary Observations / Christopher Skisak, John DiGiovanni, Claudio J. Conti, Thomas J. Slaga, Sheela Sharma, John W. Sagartz and Earl F. Walborg, Jr.
  • Incorporating the Concept of "Invaders" and "Defenders" in the Dose-Response Modeling of Carcinogens / Donald E. Stevenson and Robert L. Sielken, Jr.