Autophagy in tumor and tumor microenvironment /

Saved in:
Bibliographic Details
Imprint:Singapore : Springer, [2020]
Description:1 online resource (vii, 280 pages) : color illustrations
Language:English
Subject:Cancer cells.
Cancer -- Research.
Cancer -- Genetic aspects.
Immunology.
Drug resistance.
Gene expression.
Stem cells.
Apoptosis.
Neoplasms.
Cancer -- Genetic aspects.
Cancer cells.
Apoptosis.
Cancer -- Research.
Drug resistance.
Gene expression.
Immunology.
Stem cells.
Electronic books.
Electronic books.
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/12608111
Hidden Bibliographic Details
Other authors / contributors:Bhutia, Sujit Kumar, editor.
ISBN:9789811569302
9811569304
9811569290
9789811569296
Digital file characteristics:text file PDF
Notes:Includes bibliographical references.
Print version record.
Summary:This book deals with the paradoxical role of autophagy in tumor suppression and tumor promotion in cancer cells. Autophagy plays opposing, context-dependent roles in tumors; accordingly, strategies based on inhibiting or stimulating autophagy could offer as potential cancer therapies. The book elucidates the physiological role of autophagy in modulating cancer metastasis, which is the primary cause of cancer-associated mortality. Further, it reviews its role in the differentiation, development, and activation of multiple immune cells, and its potential applications in tumor immunotherapy. In addition, it examines the effect of epigenetic modifications of autophagy-associated genes in regulating tumor growth and therapeutic response and summarizes autophagy's role in the development of resistance to a variety of anti-cancer drugs in cancer cells. In closing, it assesses autophagy as a potential therapeutic target for cancer treatment. Given its scope, the book offers a valuable asset for all oncologists and researchers who wish to understand the potential role of autophagy in tumor biology.
Other form:Original 9811569290 9789811569296
Standard no.:10.1007/978-981-15-6930-2