Palladium and nickel catalyzed transformations forming functionalized heterocycles /

Palladium and nickel catalyzed transformations forming functionalized heterocycles /

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Bibliographic Details
Author / Creator:	Yoon, Hyung.
Imprint:	Cham : Springer, 2020.
Description:	1 online resource (xxix, 212 pages) : illustrations (some color)
Language:	English
Series:	Springer Theses Springer theses.
Subject:	Heterocyclic compounds. Catalysis. Chemistry, Inorganic. Chemistry, Organic. Organometallic chemistry. Chemistry, Physical and theoretical. Catalysis. Chemistry, Inorganic. Chemistry, Organic. Chemistry, Physical and theoretical. Heterocyclic compounds. Organometallic chemistry.
Format:	E-Resource Book
URL for this record:	http://pi.lib.uchicago.edu/1001/cat/bib/12607857

Hidden Bibliographic Details
ISBN:	9783030540777 3030540774 9783030540760 3030540766
Notes:	Includes bibliographical references.
Summary:	This book presents Pd- and Ni-catalyzed transformations generating functionalized heterocycles. Transition metal catalysis is at the forefront of synthetic organic chemistry since it offers new and powerful methods to forge carbon-carbon bonds in high atom- and step-economy. In Chapter 1, the author describes a Pd- and Ni-catalyzed cycloisomerization of aryl iodides to alkyl iodides, known as carboiodination. In the context of the Pd-catalyzed variant, the chapter explores the production of enantioenriched carboxamides through diastereoselective Pd-catalyzed carboiodination. It then discusses Ni-catalyzed reactions to generate oxindoles and an enantioselective variant employing a dual ligand system. Chapter 2 introduces readers to a Pd-catalyzed diastereoselective anion-capture cascade. It also examines diastereoselective Pd-catalyzed aryl cyanation to synthesize alkyl nitriles, a method that generates high yields of borylated chromans as a single diastereomer, and highlights its synthetic utility. Lastly, Chapter 3 presents a Pd-catalyzed domino process harnessing carbopalladation, C-H activation and π-system insertion (benzynes and alkynes) to generate spirocycles. It also describes the mechanistic studies performed on these reactions.
Other form:	Print version: Yoon, Hyung Palladium and Nickel Catalyzed Transformations Forming Functionalized Heterocycles Cham : Springer International Publishing AG,c2020 9783030540760
Standard no.:	10.1007/978-3-030-54077-7 10.1007/978-3-030-54

Description
Summary:	This book presents Pd- and Ni-catalyzed transformations generating functionalized heterocycles. Transition metal catalysis is at the forefront of synthetic organic chemistry since it offers new and powerful methods to forge carbon-carbon bonds in high atom- and step-economy. In Chapter 1, the author describes a Pd- and Ni-catalyzed cycloisomerization of aryl iodides to alkyl iodides, known as carboiodination. In the context of the Pd-catalyzed variant, the chapter explores the production of enantioenriched carboxamides through diastereoselective Pd-catalyzed carboiodination. It then discusses Ni-catalyzed reactions to generate oxindoles and an enantioselective variant employing a dual ligand system. Chapter 2 introduces readers to a Pd-catalyzed diastereoselective anion-capture cascade. It also examines diastereoselective Pd-catalyzed aryl cyanation to synthesize alkyl nitriles, a method that generates high yields of borylated chromans as a single diastereomer, andhighlights its synthetic utility. Lastly, Chapter 3 presents a Pd-catalyzed domino process harnessing carbopalladation, C-H activation and π-system insertion (benzynes and alkynes) to generate spirocycles. It also describes the mechanistic studies performed on these reactions.
Physical Description:	1 online resource (xxix, 212 pages) : illustrations (some color)
Bibliography:	Includes bibliographical references.
ISBN:	9783030540777 3030540774 9783030540760 3030540766