Palladium and nickel catalyzed transformations forming functionalized heterocycles /

Saved in:
Bibliographic Details
Author / Creator:Yoon, Hyung.
Imprint:Cham : Springer, 2020.
Description:1 online resource (xxix, 212 pages) : illustrations (some color)
Series:Springer Theses
Springer theses.
Subject:Heterocyclic compounds.
Chemistry, Inorganic.
Chemistry, Organic.
Organometallic chemistry.
Chemistry, Physical and theoretical.
Inorganic chemistry.
Organic chemistry.
Organometallic chemistry.
Physical chemistry.
Science -- Chemistry -- Inorganic.
Science -- Chemistry -- Organic.
Science -- Chemistry -- Physical & Theoretical.
Science -- Chemistry -- Industrial & Technical.
Chemistry, Inorganic.
Chemistry, Organic.
Chemistry, Physical and theoretical.
Heterocyclic compounds.
Organometallic chemistry.
Electronic books.
Format: E-Resource Book
URL for this record:
Hidden Bibliographic Details
Notes:Includes bibliographical references.
Summary:This book presents Pd- and Ni-catalyzed transformations generating functionalized heterocycles. Transition metal catalysis is at the forefront of synthetic organic chemistry since it offers new and powerful methods to forge carbon-carbon bonds in high atom- and step-economy. In Chapter 1, the author describes a Pd- and Ni-catalyzed cycloisomerization of aryl iodides to alkyl iodides, known as carboiodination. In the context of the Pd-catalyzed variant, the chapter explores the production of enantioenriched carboxamides through diastereoselective Pd-catalyzed carboiodination. It then discusses Ni-catalyzed reactions to generate oxindoles and an enantioselective variant employing a dual ligand system. Chapter 2 introduces readers to a Pd-catalyzed diastereoselective anion-capture cascade. It also examines diastereoselective Pd-catalyzed aryl cyanation to synthesize alkyl nitriles, a method that generates high yields of borylated chromans as a single diastereomer, and highlights its synthetic utility. Lastly, Chapter 3 presents a Pd-catalyzed domino process harnessing carbopalladation, C-H activation and π-system insertion (benzynes and alkynes) to generate spirocycles. It also describes the mechanistic studies performed on these reactions.
Other form:Print version: Yoon, Hyung Palladium and Nickel Catalyzed Transformations Forming Functionalized Heterocycles Cham : Springer International Publishing AG,c2020 9783030540760
Standard no.:10.1007/978-3-030-54077-7