Nucleotide analogues as antiviral agents /

Nucleotide analogues as antiviral agents /

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Bibliographic Details
Imprint:Washington, DC : American Chemical Society, 1989.
Description:1 online resource (204 pages) : illustrations.
Language:English
Series:ACS symposium series, 1947-5918 ; 401
ACS symposium series ; 401.
Subject:
Antiviral agents -- Testing.
Antiviral agents -- Synthesis.
Antiviral agents -- Evaluation.
Nucleotides -- Derivatives -- Therapeutic use -- Testing.
Reverse transcriptase -- Inhibitors.
Phosphonates -- Synthesis.
DNA viruses -- Treatment.
Nucleotides -- Synthesis.
Heterocyclic compounds -- Derivatives.
Herpes simplex virus -- Inhibitors.
Glycosylation -- Inhibitors.
Semliki Forest virus -- Analysis.
Ribavirin -- Analysis.
AIDS (Disease) -- Analysis.
Chemotherapy -- Analysis.
Antiviral Agents -- pharmacology.
Nucleotides -- pharmacology.
Antiviral Agents -- chemical synthesis.
Nucleotides -- therapeutic use.
Reverse Transcriptase Inhibitors.
Phosphonates -- chemical synthesis.
DNA Virus Infections -- therapy.
Nucleotides -- chemical synthesis.
Heterocyclic Compounds.
Herpes Simplex.
Glycosylation.
Semliki forest virus.
Ribavirin -- analysis.
Acquired Immunodeficiency Syndrome.
Drug Therapy.
Format: E-Resource Book
Local Note:American Chemical Society, ACS Symposium Series eBooks - 1989 Front Files.
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/12564848
Hidden Bibliographic Details
Other authors / contributors:Martin, John C., 1951- editor. Bristol-Myers Company.
American Chemical Society. Division of Carbohydrate Chemistry, sponsoring body.
American Chemical Society. Division of Medicinal Chemistry, sponsoring body.
American Chemical Society. Meeting (196th : 1988 : Los Angeles, California)
ISBN:9780841212527
Notes:"Developed from a symposium sponsored by the Division of Carbohydrate Chemistry and the Division of Medicinal Chemistry at the 196th National Meeting of the American Chemical Society, Los Angeles, California, September 25-30, 1988."
Distributed in print by Oxford University Press.
Includes bibliographical references and index.
Description based on publisher-supplied information and home-page.
Other form:Original 9780841216594 (alk. paper)
Original 0841216592 (alk. paper)
Online version
Standard no.:bk-1989-0401
Table of Contents:
  • Inhibitors of Viral Nucleic Acid Polymerases: Pyrophosphate Analogues / McKenna, Charles E., Department of Chemistry, University of Southern California, Los Angeles, CA 90089-0744; Levy, Jeffrey N., Department of Chemistry, University of Southern California, Los Angeles, CA 90089-0744; Khawli, Leslie A., Department of Chemistry, University of Southern California, Los Angeles, CA 90089-0744, Current address: Department of Pathology, School of Medicine, University of Southern California, Los Angeles, CA 90033; Harutunian, Vahak, Department of Pharmacology and Medicine, School of Medicine, University of North Carolina-Chapel Hill, Chapel Hill, NC 27514; Ye, Ting-Gao, Department of Chemistry, University of Southern California, Los Angeles, CA 90089-0744, Current address: Wenzhou Institute of Pesticide Research, Huiqiaopu, Wenzhou, Zhejiang, China; Starnes, Milbrey C., Department of Pharmacology and Medicine, School of Medicine, University of North Carolina-Chapel Hill, Chapel Hill, NC 27514; Bapat, Ashok, Department of Pharmacology and Medicine, School of Medicine, University of North Carolina-Chapel Hill, Chapel Hill, NC 27514, Current address: Wyeth Laboratories, P.O. Box 8299, Philadelphia, PA 19101-82; Cheng, Yung-Chi, Department of Pharmacology and Medicine, School of Medicine, University of North Carolina-Chapel Hill, Chapel Hill, NC 27514, Current address: Department of Pharmacology, School of Medicine, Yale University, New Haven, CT 06510 / http://dx.doi.org/10.1021/bk-1989-0401.ch001
  • Synthesis of Acyclonucleoside Phosphonates for Evaluation as Antiviral Agents / Reist, E. J., Life Sciences Division, SRI International, Menlo Park, CA 94025; Sturm, P. A., Life Sciences Division, SRI International, Menlo Park, CA 94025; Pong, R. Y., Life Sciences Division, SRI International, Menlo Park, CA 94025; Tanga, M. J., Life Sciences Division, SRI International, Menlo Park, CA 94025; Sidwell, R. W., Utah State University, Logan, UT 84322-0300 / http://dx.doi.org/10.1021/bk-1989-0401.ch002
  • Structural Requirements for Enzymatic Activation of Acyclonucleotide Analogues: Relationship to Their Mode of Antiherpetic Action / Tolman, Richard L. / http://dx.doi.org/10.1021/bk-1989-0401.ch003
  • Phosphonylmethyl Ethers of Nucleosides and Their Acyclic Analogues / Holý, Antonin, Institute of Organic Chemistry and Biochemistry, Czechoslovak Academy of Sciences, 166 10 Praha 6, Czechoslovakia; De Clercq, Erik, Rega Institute, Katholieke Universiteit Leuven, Minderbroedersstraat 10, B-3000 Leuven, Belgium; Votruba, Ivan, Institute of Organic Chemistry and Biochemistry, Czechoslovak Academy of Sciences, 166 10 Praha 6, Czechoslovakia / http://dx.doi.org/10.1021/bk-1989-0401.ch004
  • Synthesis and Antiviral Activity of Phosphonylmethoxyethyl Derivatives of Purine and Pyrimidine Bases / Bronson, Joanne J., Bristol-Myers Company, Pharmaceutical Research and Development Division, 5 Research Parkway, Wallingford, CT 06492-7660; Kim, Choung Un, Bristol-Myers Company, Pharmaceutical Research and Development Division, 5 Research Parkway, Wallingford, CT 06492-7660; Ghazzouli, Ismail, Bristol-Myers Company, Pharmaceutical Research and Development Division, 5 Research Parkway, Wallingford, CT 06492-7660; Hitchcock, Michael J. M., Bristol-Myers Company, Pharmaceutical Research and Development Division, 5 Research Parkway, Wallingford, CT 06492-7660; Kern, Earl R., University of Alabama, Birmingham, AL 35294; Martin, John C., Bristol-Myers Company, Pharmaceutical Research and Development Division, 5 Research Parkway, Wallingford, CT 06492-7660 / http://dx.doi.org/10.1021/bk-1989-0401.ch005
  • Synthesis and Antiviral Activity of Nucleotide Analogues Bearing the (S)-(3-Hydroxy-2-phosphonylmethoxy)propyl Moiety Attached to Adenine, Guanine, and Cytosine / Bronson, Joanne J., Bristol-Myers Company, Pharmaceutical Research and Development Division, 5 Research Parkway, Wallingford, CT 06492-7660; Ghazzouli, Ismail, Bristol-Myers Company, Pharmaceutical Research and Development Division, 5 Research Parkway, Wallingford, CT 06492-7660; Hitchcock, Michael J. M., Bristol-Myers Company, Pharmaceutical Research and Development Division, 5 Research Parkway, Wallingford, CT 06492-7660; Webb, Robert R., Bristol-Myers Company, Pharmaceutical Research and Development Division, 5 Research Parkway, Wallingford, CT 06492-7660; Kern, Earl R., University of Alabama, Birmingham, AL 35294; Martin, John C., Bristol-Myers Company, Pharmaceutical Research and Development Division, 5 Research Parkway, Wallingford, CT 06492-7660 / http://dx.doi.org/10.1021/bk-1989-0401.ch006
  • Design of Inhibitors of Herpes Simplex Virus Thymidine Kinase / Martin, J. A.; Duncan, I. B.; Thomas, G. J. / http://dx.doi.org/10.1021/bk-1989-0401.ch007
  • Nucleotides as Herpesvirus-Specific Inhibitors of Protein Glycosylation / Datema, Roelf, Bristol-Myers Company, Pharmaceutical Research and Development Division, 5 Research Parkway, Wallingford, CT 06492-7660; Olofsson, Sigvard, Göteborgs Universitet, Department of Clinical Virology, Guldhedsgatan 10B, S-41346 Göteborg, Sweden / http://dx.doi.org/10.1021/bk-1989-0401.ch008
  • Antiviral Activity of the Nucleotide Analogue Ribavirin 5'-Sulfamate / Smee, Donald F. / http://dx.doi.org/10.1021/bk-1989-0401.ch009
  • Design, Synthesis, and Antiviral Activity of Nucleoside and Nucleotide Analogues / Marquez, Victor E. / http://dx.doi.org/10.1021/bk-1989-0401.ch010
  • Nucleotide Dimers as Anti Human Immunodeficiency Virus Agents / Hahn, Elliot F., IVAX Corporation, 8800 NW 36th Street, Miami, FL 33178; Busso, Mariano, Departments of Dermatology and Pathology, Mount Sinai Medical Center, 4300 Alton Road, Miami Beach, FL 33140; Mian, Abdul M., Department of Oncology, University of Miami Medical School, Miami, FL 33131; Resnick, Lionel, Departments of Dermatology and Pathology, Mount Sinai Medical Center, 4300 Alton Road, Miami Beach, FL 33140 / http://dx.doi.org/10.1021/bk-1989-0401.ch011
  • Oligonucleotide Analogues as Potential Chemotherapeutic Agents / Zon, G. / http://dx.doi.org/10.1021/bk-1989-0401.ch012

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