Aneurysms-osteoarthritis syndrome : SMAD3 gene mutations /

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Bibliographic Details
Author / Creator:Linde, Denise van der
Imprint:London : Academic Press, [2017]
©2017
Description:1 online resource
Language:English
Subject:Aneurysms -- Genetic aspects.
Osteoarthritis -- Genetic aspects.
Molecular biology.
MEDICAL -- Genetics.
Molecular biology.
Aortic Aneurysm, Thoracic.
Osteoarthritis.
Smad3 Protein -- genetics.
Mutation -- genetics.
Aortic Diseases -- diagnosis.
Thoracic Diseases -- diagnosis.
Genetic Diseases, Inborn -- diagnosis.
Diagnosis, Differential.
Electronic books.
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/11736234
Hidden Bibliographic Details
Other authors / contributors:Roos-Hesselink, Jolien, author.
Loeys, Bart L., author.
ISBN:9780128027110
0128027118
9780128027080
0128027088
Notes:Includes bibliographical references and index.
Online resource, title from PDF title page (EBSCO, viewed October 23, 2016).
Other form:Print version: Van Derlinde, Denise. Aneurysms-osteoarthritis syndrome : smad3 gene mutations. Amsterdam, [Netherlands] : Academic Press, ©2017 xiii, 163 pages 9780128027080
Description
Summary:<p> Aneurysms-Osteoarthritis Syndrome: SMAD3 Gene Mutations is a first-of-its-kind compilation of the genetic discovery, research, and care associated with AOS. With the field of genetically triggered aortopathies growing, this important reference will compile the newest discoveries in this field, allowing cardiologists, cardio-thoracic surgeons, clinical geneticists, vascular surgeons, orthopedic surgeons, and researchers to gain the knowledge they need without having to gather the data from various sources.</p> <p>Coverage includes genotype and phenotype correlations, the functional role of SMAD3, and insights into the role of TGFbeta signaling in aortic disease. The book will increase knowledge about AOS, providing awareness and better patient care for this aggressive disease.</p> Covers Aneurysms-Osteoarthritis Syndrome, from genetic discovery to patient care Contains clinical management guidance on optimal cardiovascular treatments and surgery Explains the autosomal dominant syndromes caused by mutations in the SMAD3 gene Identifies the key features of this syndrome, including arterial aneurysms and tortuosity, early onset arthritis, and mild craniofacial features
Physical Description:1 online resource
Bibliography:Includes bibliographical references and index.
ISBN:9780128027110
0128027118
9780128027080
0128027088