Targeting protein-protein interactions by small molecules /

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Bibliographic Details
Imprint:Singapore : Springer, 2018.
Description:1 online resource
Language:English
Subject:Protein-protein interactions.
Molecular association.
Biochemistry.
SCIENCE -- Life Sciences -- Biochemistry.
Biochemistry.
Molecular association.
Protein-protein interactions.
Chemistry.
Medicinal Chemistry.
Pharmaceutical Sciences/Technology.
Bioorganic Chemistry.
Protein Science.
Electronic books.
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/11664456
Hidden Bibliographic Details
Other authors / contributors:Sheng, Chunquan, editor.
Georg, Gunda I., editor.
ISBN:9789811307737
9811307733
9789811307720
9811307725
9789811307744
9811307741
9789811344961
9811344965
Digital file characteristics:text file PDF
Notes:Online resource; title from PDF title page (EBSCO, viewed July 1, 2018).
Summary:This book comprehensively reviews the state-of-the-art strategies developed for protein-protein interaction (PPI) inhibitors, and highlights the success stories in new drug discovery and development. Consisting of two parts with twelve chapters, it demonstrates the design strategies and case studies of small molecule PPI inhibitors. The first part discusses various discovery strategies for small molecule PPI inhibitors, such as high throughput screening, hot spot-based design, computational approaches, and fragment-based design. The second part presents recent advances in small molecule inhibitors, focusing on clinical candidates and new PPI targets. This book has broad appeal and is of significant interest to the pharmaceutical science and medicinal chemistry communities.
Other form:Print version: Targeting protein-protein interactions by small molecules. Singapore : Springer, 2018 9811307725 9789811307720
Standard no.:10.1007/978-981-13-0773-7
10.1007/978-981-13-0