Irreversible electroporation in clinical practice /

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Bibliographic Details
Imprint:	Cham, Switzerland : Springer, 2018.
Description:	1 online resource : illustrations
Language:	English
Subject:	Computer-assisted surgery. Electroporation. Laser ablation. Electrochemotherapy -- methods. Ablation Techniques -- methods. Neoplasms -- drug therapy. Computer-assisted surgery. Electroporation. Laser ablation. Electronic books.
Format:	E-Resource Book
URL for this record:	http://pi.lib.uchicago.edu/1001/cat/bib/11542914

Hidden Bibliographic Details
Other authors / contributors:	Meijerink, Martijn R., editor. Scheffer, Hester J., editor. Narayanan, Govindarajan, editor.
ISBN:	9783319551135 3319551132 9783319551128 3319551124
Digital file characteristics:	text file PDF
Notes:	Includes bibliographical references and index. Vendor-supplied metadata.
Summary:	This book provides a comprehensive overview of the clinical use of irreversible electroporation (IRE)- better known by its commercial name, NanoKnife- which is one of the most exciting new needle-guided cancer treatments. The coverage includes the history of IRE, general technique, preclinical research, applications in clinical practice and early clinical results, and future perspectives. Contraindications, treatment planning, potential complications, follow-up imaging, and other practical aspects are fully discussed, with highlighting of useful tips and tricks. Through the delivery of short but highly intense electrical pulses, IRE results in tumor cell membrane permeabilization, causing cells to go into apoptosis. The minimally invasive nature of IRE, combined with the prospect of completely eradicating tumors while preserving delicate structures in the ablation zone, makes IRE the object of worldwide clinical research. This book will be of value for practitioners and trainees in interventional and diagnostic radiology, surgery, medical oncology, HPB and gastroenterology, urology, and radiation oncology.
Other form:	Print version: Irreversible electroporation in clinical practice. Cham, Switzerland : Springer, 2018 3319551124 9783319551128
Standard no.:	10.1007/978-3-319-55113-5

Table of Contents:

Introduction: History of image-guided tumor ablation
History of electroporation. Preclinical Research: Multi-scale biophysical principles in clinical irreversible electroporation
Numerical modelling for prediction and evaluation of treatment outcome
The effect of irreversible electroporation on blood vessels, bile ducts, urinary tract, intestines and nerves. Technique, tips and tricks: Anaesthetic management during irreversible electroporation procedure
Complications and procedures to enhance safety
Treatment planning, needle insertion, image-guidance, endpoint Assessment
Thermal effects of irreversible electroporation
Clinical practice: Irreversible electroporation of liver tumors
Irreversible electroporation of pancreatic tumors
Irreversible electroporation for perihilar cholangiocarcinoma (Klatskin tumors)
Irreversible electroporation of kidney tumors
Irreversible Electroporation of Prostate Tumors
Irreversible electroporation of tumors within the pelvic cavity
Irreversible Electroporation of Lung Tumors
Future prospectives: From local to systemic treatment: leveraging antitumor immunity following irreversible electroporation
Future perspectives of IRE.

Irreversible electroporation in clinical practice /

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