Hidden Bibliographic Details
| Other authors / contributors: | Knott, Jason.
Latham, Keith.
|
|---|
| ISBN: | 9783319631875
331963187X
9783319631868
3319631861
|
|---|
| Digital file characteristics: | text file PDF
|
|---|
| Notes: | Includes bibliographical references.
Print version record.
|
|---|
| Summary: | Five leaders in the field of mammalian preimplantation embryo development provide their own perspectives on key molecular and cellular processes that mediate lineage formation during the first week of life. The first cell-fate decision involves the formation of the pluripotent inner cell mass (ICM) and extraembryonic trophectoderm (TE). The second cell-fate choice encompasses the transformation of ICM into extraembryonic primitive endoderm (PE) and pluripotent epiblast. The processes, which occur during the period of preimplantation development, serve as the foundation for subsequent developmental events such as implantation, placentation, and gastrulation. The mechanisms that regulate them are complex and involve many different factors operating spatially and temporally over several days to modulate embryonic chromatin structure, impose cellular polarity, and direct distinct gene expression programs in the first cell lineages.
|
|---|
| Other form: | Print version: Knott, Jason. Chromatin Regulation of Early Embryonic Lineage Specification. Cham : Springer International Publishing AG, z. Hd. Alexander Grossmann, ©2017 9783319631868
|
|---|
| Standard no.: | 10.1007/978-3-319-63187-5
10.1007/978-3-319-63
|
|---|
