Surface-enhanced raman spectroscopy : bioanalytical, biomolecular and medical applications /

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Bibliographic Details
Author / Creator:Procházka, Marek, author.
Imprint:Cham : Springer, 2016.
Description:1 online resource : chiefly color illustrations
Series:Biological and medical physics, biomedical engineering, 2197-5647
Biological and medical physics, biomedical engineering.
Subject:Raman spectroscopy.
Raman effect, Surface enhanced.
Biology, life sciences.
Spectrum analysis, spectrochemistry, mass spectrometry.
Mensuration & systems of measurement.
Medical physics.
SCIENCE -- Chemistry -- Analytic.
Raman effect, Surface enhanced.
Raman spectroscopy.
Electronic books.
Electronic books.
Format: E-Resource Book
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Digital file characteristics:text file PDF
Notes:Includes bibliographical references and index.
Online resource; title from PDF title page (EBSCO, viewed December 17, 2015).
Summary:This book gives an overview of recent developments in RS and SERS for sensing and biosensing considering also limitations, possibilities and prospects of this technique. Raman scattering (RS) is a widely used vibrational technique providing highly specific molecular spectral patterns. A severe limitation for the application of this spectroscopic technique lies in the low cross section of RS. Surface-enhanced Raman scattering (SERS) spectroscopy overcomes this problem by 6-11 orders of magnitude enhancement compared with the standard RS for molecules in the close vicinity of certain rough metal surfaces. Thus, SERS combines molecular fingerprint specificity with potential single-molecule sensitivity. Due to the recent development of new SERS-active substrates, labeling and derivatization chemistry as well as new instrumentations, SERS became a very promising tool for many varied applications, including bioanalytical studies and sensing. Both intrinsic and extrinsic SERS biosensing schemes have been employed to detect and identify small molecules, nucleic acids and proteins, and also for cellular and in vivo sensing.
Other form:Printed edition: 9783319239903
Standard no.:10.1007/978-3-319-23992-7