Gene therapy of solid cancers : methods and protocols /

Gene therapy of solid cancers : methods and protocols /

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Bibliographic Details
Imprint:New York, NY : Humana Press, [2015]
©2015
Description:1 online resource (xiii, 387 pages) : illustrations (some color)
Language:English
Series:Methods in molecular biology, 1940-6029 ; 1317
Methods in molecular biology (Clifton, N.J.) ; v. 1317.
Subject:
Cancer -- Gene therapy -- Laboratory manuals.
Genetic Therapy -- methods.
Neoplasms -- therapy.
Cancer -- Gene therapy.
Laboratory manuals.
Electronic books.
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/11243192
Hidden Bibliographic Details
Other authors / contributors:Walther, Wolfgang, editor.
Stein, Ulrike, editor.
ISBN:9781493927272
1493927272
1493927264
9781493927265
9781493927265
Notes:Includes bibliographical references and index.
Online resource; title from PDF title page (SpringerLink, viewed June 19, 2015).
Summary:This volume provides insight into recent developments on experimental and clinical strategies for cancer gene therapy. Gene Therapy of Solid Cancers: Methods and Protocols guides readers through protocols on gene therapeutic strategies in combination with helpful technical notes. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.
Other form:Print version: Gene therapy of solid cancers. New York, NY : Humana Press, [2015]
Standard no.:10.1007/978-1-4939-2727-2
Table of Contents:
  • Aptamer targeting the ERBB2 receptor tyrosine kinase for applications in tumor therapy / Georg Mahlknecht, Michael Sela, and Yosef Yarden
  • Gene gun her2/neu DNA vaccination : evaluation of vaccine efficacy in a syngeneic her2/neu mouse tumor model / Tam Nguyen-Hoai, Antonio Pezzutto, and Jörg Westermann
  • MIDGE technology for the production of a fourfold gene-modified, allogenic cell-based vaccine for cancer therapy / Manuel Schmidt, Barbara Volz, Patrick Grossmann, Kerstin Heinrich, and Burghardt Wittig
  • Evaluation of bystander cell killing effects in suicide gene therapy of cancer : engineered thymidylate kinase (TMPK)/AZT enzyme-prodrug axis / Takeya Sato, Anton Neschadim, Ryo Nakagawa, Teruyuki Yanagisawa, and Jeffrey A. Medin
  • Oncoleaking : use of the pore-forming Clostridium perfringens enterotoxin (CPE) for suicide gene therapy / Jessica Pahle, Jutta Aumann, Dennis Kobelt, and Wolfgang Walther
  • iCaspase 9 suicide gene system / Xiaoou Zhou, Antonio Di Stasi, and Malcolm K. Brenner
  • p53-encoding pDNA purification by affinity chromatography for cancer therapy / Ângela Sousa, João A. Queiroz, and Fani Sousa.
  • Phase 2, open-label, randomized study of pexa-vec (JX-594) administered by intratumoral injection in patients with unresectable primary hepatocellular carcinoma / Caroline J. Breitbach, Anne Moon, James Burke, Tae-Ho Hwang, and David H. Kirn
  • Antiangiogenic metargidin peptide (AMEP) tene therapy in disseminated melanoma / Iben Spanggaard and Julie Gehl
  • Clinical evaluation of ErbB-targeted CAR T-cells, rollowing intracavity delivery in patients with ErbB-expressing solid tumors / Sophie Papa, May van Schalkwyk, and John Maher.

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