RNA turnover in eukaryotes : analysis of specialized and quality control RNA decay pathways /

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Bibliographic Details
Imprint:San Diego, Calif. : Academic, 2008.
Description:1 online resource (xliv, 417 pages, [1] leaf of plates) : illustrations (some color).
Series:Methods in enzymology, 0076-6879 ; v. 449
Methods in enzymology ; volume 449.
RNA Precursors.
RNA Stability -- physiology.
Eukaryotic Cells -- metabolism.
RNA, Messenger -- metabolism.
mRNA Cleavage and Polyadenylation Factors.
SCIENCE -- Life Sciences -- Biology.
SCIENCE -- Life Sciences -- Microbiology.
Laboratory Manuals.
Electronic books.
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/11195230
Hidden Bibliographic Details
Varying Form of Title:Analysis of specialized and quality control RNA decay pathways
Other authors / contributors:Maquat, Lynne.
Kiledjian, Megerditch.
Notes:Includes bibliographical references and indexes.
Print version record.
Summary:Specific complexes of protein and RNA carry out many essential biological functions, including RNA processing, RNA turnover, RNA folding, as well as the translation of genetic information from mRNA into protein sequences. Messenger RNA (mRNA) decay is now emerging as an important control point and a major contributor to gene expression. Continuing identification of the protein factors and cofactors, and mRNA instability elements responsible for mRNA decay allow researchers to build a comprehensive picture of the highly orchestrated processes involved in mRNA decay and its regulation. * Covers the nonsense-mediated mRNA decay (NMD) or mRNA surveillance pathway * Expert researchers introduce the most advanced technologies and techniques * Offers step-by-step lab instructions, including necessary equipment and reagents.
Other form:Print version: RNA turnover in eukaryotes
Print version: RNA turnover in eukaryotes. San Diego, Calif. : Academic, 2008 9780123745842 0123745845