Principles of nucleic acid structure /

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Bibliographic Details
Author / Creator:Neidle, Stephen.
Edition:1st ed.
Imprint:Amsterdam : Elsevier ; Boston : Academic Press, 2008.
Description:1 online resource (xii, 289 pages) : illustrations
Language:English
Subject:Nucleic acids.
Nucleic Acid Conformation
Nucleic Acids -- chemistry
Acides nucléiques.
SCIENCE -- Chemistry -- Organic.
Nucleic acids.
Molekulargenetik
Electronic books.
Electronic books.
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/11164043
Hidden Bibliographic Details
ISBN:9780123695079
0123695074
9780080553528
0080553524
1281059374
9781281059376
9786611059378
6611059377
Digital file characteristics:data file
Notes:Includes bibliographical references and index.
Restrictions unspecified
Electronic reproduction. [Place of publication not identified] : HathiTrust Digital Library, 2010.
Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. http://purl.oclc.org/DLF/benchrepro0212
English.
digitized 2010 HathiTrust Digital Library committed to preserve
Print version record.
Summary:This unique and practical resource provides the most complete and concise summary of underlying principles and approaches to studying nucleic acid structure, including discussion of x-ray crystallography, NMR, molecular modelling, and databases. Its focus is on a survey of structures especially important for biomedical research and pharmacological applications. To aid novices, the book includes an introduction to technical lingo used to describe nucleic acid structure and conformations (roll, slide, twist, buckle, etc.). This completely updated edition features expanded coverage of the latest advances relevant to recognition of DNA and RNA by small molecules and proteins. In particular, the reader will find extensive new discussions on: RNA folding, ribosome structure and antibiotic interactions, DNA quadruplexes, DNA and RNA protein complexes, and short interfering RNA (siRNA). This handy guide ends with a complete list of resources, including relevant online databases and software. * Completely updated with expanded discussion of topics such as RNA folding, ribosome structure and antibiotic interactions, DNA quadruplexes, DNA and RNA protein complexes, and short interfering RNA (siRNA) * Includes a complete list of resources, including relevant online databases and software * Defines technical lingo for novices.
Other form:Print version: Neidle, Stephen. Principles of nucleic acid structure. 1st ed. Amsterdam : Elsevier ; Boston : Academic Press, 2008 9780123695079 0123695074