Genetic recombination : reviews and protocols /

Saved in:
Bibliographic Details
Imprint:Totowa, N.J. : Humana Press, ©2004.
Description:1 online resource (x, 260 pages) : illustrations (some color)
Series:Methods in molecular biology, 1064-3745 ; v. 262
Methods in molecular biology (Clifton, N.J.) ; v. 262.
Subject:Genetic recombination.
Recombination, Genetic.
Gene Expression.
Gene Targeting.
Genetic Engineering.
SCIENCE -- Life Sciences -- Molecular Biology.
Genetic recombination.
Electronic books.
Format: E-Resource Book
URL for this record:
Hidden Bibliographic Details
Other authors / contributors:Waldman, Alan S.
Notes:Includes bibliographical references and index.
Print version record.
Summary:Genetic recombination plays an essential role in such vitally important biological processes as DNA repair, regulation of gene expression, disease etiology, meiotic chromosome segregation, and evolution. In Genetic Recombination: Reviews and Protocols, prominent international investigators actively engaged in recombination research describe in great detail their best techniques for studying recombination. The methods range from approaches and model systems to be used in a variety of eukaryotic organisms and in a mammalian parasite, to biochemical analyses useful for furthering the understanding of recombination mechanisms. Additional techniques use recombination as a reporter of genomic instability in lower and higher eukaryotes and as a tool for producing targeted genetic modification. Each readily reproducible method includes step-by-step instructions, a background introduction outlining the principle behind the technique, lists of equipment and reagents, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and highly practical, Genetic Recombination: Reviews and Protocols offers both novice and experienced investigators an illuminating synthesis of what we currently know about recombination, as well as a wide-ranging collection of powerful tools for elucidating its mechanisms and regulation throughout biology today.
Other form:Genetic recombination
Standard no.:10.1385/1592597610.