Suicide gene therapy : methods and reviews /

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Bibliographic Details
Imprint:Totowa, N.J. : Humana Press, ©2004.
Description:1 online resource (xiv, 555 pages) : illustrations (some color)
Series:Methods in molecular medicine, 1543-1894 ; 90
Methods in molecular medicine ; 90.
Subject:Cancer -- Gene therapy.
Neoplasms -- therapy.
Genetic Therapy -- methods.
Genes, Transgenic, Suicide.
MEDICAL -- Oncology.
HEALTH & FITNESS -- Diseases -- Cancer.
Cancer -- Gene therapy.
Electronic books.
Format: E-Resource Book
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Other authors / contributors:Springer, Caroline J.
Notes:Includes bibliographical references and index.
Print version record.
Summary:Suicide gene therapy has become a major element in anticancer gene therapy and holds great promise for the future. In Suicide Gene Therapy: Methods and Reviews, prominent researchers and clinicians comprehensively detail the theory and practice of this exciting and elegant therapeutic approach. In their multidisciplinary treatment, the authors cover all the major aspects of suicide gene therapy, including the design and use of vectors in gene transduction, various enzyme and prodrug systems, the mechanistic analysis of the bystander effect, the design and synthesis of prodrugs, the immunological implications, and its clinical impact. They also describe and expound upon all the cutting-edge methods needed to explore, study, and advance understanding of the basic biology underlying gene therapy. Each fully tested method includes step-by-step instructions, a discussion of the principle behind the technique, equipment and reagent lists, tips on troubleshooting and avoiding pitfalls, and notes on the interpretation and use of results. Authoritative and up-to-date, Suicide Gene Therapy: Methods and Reviews not only summarizes our knowledge of suicide gene therapy today, but also provides the experimental means to advance its future development and therapeutic applications.
Other form:Print version: Suicide gene therapy. Totowa, N.J. : Humana Press, ©2004 0896039714
Standard no.:9781592594290