Hidden Bibliographic Details
Other authors / contributors: | Efferth, Thomas, 1960- editor.
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ISBN: | 9783319098012 3319098012 9783319098005
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Notes: | Includes index. Online resource; title from PDF title page (SpringerLink, viewed November 21, 2014).
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Summary: | This critical review volume explores the theme of ABC transporters in the context of basic cancer research and its role in drug-resistant tumors. The chapters provided complement basic research by including investigations from translational applications to clinical oncology. The development of resistance is a major obstacle in cancer chemotherapy and the field has been moving rapidly in terms of determining the mechanisms for blocking ABC transporter-mediated drug efflux by specific inhibitors and thereby overcoming multidrug resistance. The volume covers these issues in careful detail. Additi.
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Other form: | Print version: Efferth, Thomas. Resistance to Targeted ABC Transporters in Cancer. Cham : Springer International Publishing, ©2014 9783319098005
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