Resistance to targeted ABC transporters in cancer /

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Bibliographic Details
Imprint:Cham : Springer, [2014]
©2015
Description:1 online resource (x, 300 pages) : illustrations (some color).
Language:English
Series:Resistance to Targeted Anti-Cancer Therapeutics, 2196-5501 ; volume 4
Resistance to targeted anti-cancer therapeutics ; v. 4.
Subject:
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/11089071
Hidden Bibliographic Details
Other authors / contributors:Efferth, Thomas, 1960- editor.
ISBN:9783319098012
3319098012
9783319098005
Notes:Includes index.
Online resource; title from PDF title page (SpringerLink, viewed November 21, 2014).
Summary:This critical review volume explores the theme of ABC transporters in the context of basic cancer research and its role in drug-resistant tumors. The chapters provided complement basic research by including investigations from translational applications to clinical oncology. The development of resistance is a major obstacle in cancer chemotherapy and the field has been moving rapidly in terms of determining the mechanisms for blocking ABC transporter-mediated drug efflux by specific inhibitors and thereby overcoming multidrug resistance. The volume covers these issues in careful detail. Additi.
Other form:Print version: Efferth, Thomas. Resistance to Targeted ABC Transporters in Cancer. Cham : Springer International Publishing, ©2014 9783319098005