Intrinsically disordered proteins /

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Bibliographic Details
Author / Creator:Uversky, Vladimir N., author.
Imprint:Cham : Springer, 2014.
Description:1 online resource (xv, 61 pages) : illustrations (some color).
Language:English
Series:SpringerBriefs in molecular science. Protein folding and structure
SpringerBriefs in molecular science. Protein folding and structure,
Subject:
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/11086982
Hidden Bibliographic Details
ISBN:9783319089218
3319089218
331908920X
9783319089201
9783319089201
Notes:Includes bibliographical references.
Online resource; title from PDF title page (SpringerLink, viewed August 18, 2014).
Print version record.
Summary:In this brief, Vladimir Uversky discusses the paradigm-shifting phenomenon of intrinsically disordered proteins (IDPs) and hybrid proteins containing ordered domains and functional IDP regions (IDPRs). Beginning with an introduction to the concept of protein intrinsic disorder, Uversky then goes on to describe the peculiar amino acid sequences of IDPs, their structural heterogeneity, typical functions and disorder-based binding modes. In the final sections, Uversky discusses IDPs in human diseases and as potential drug targets. This volume provides a snapshot to researchers entering the field as well as providing a current overview for more experienced scientists in related areas.
Other form:Printed edition: 9783319089201
Standard no.:10.1007/978-3-319-08921-8