Hidden Bibliographic Details
Other authors / contributors: | Vinks, Alexander A., editor.
Derendorf, Hartmut, editor.
Mouton, Johan W., editor.
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ISBN: | 9780387756134 0387756132 9780387756127 0387756124 9780387756127
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Notes: | Includes index. Includes bibliographical references and index. Print version record.
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Summary: | Over the past decade, significant progress has been made in the theory and applications of pharmacodynamics of antimicrobial agents. On the basis of pharmacokinetic-pharmacodynamic modeling concepts it has become possible to describe and predict the time course of antimicrobial effects under normal and pathophysiological conditions. The study of pharmacokinetic-pharmacodynamic relationships can be of considerable value in understanding drug action, defining optimal dosing regimens, and in making predictions under new or changing pre-clinical and clinical circumstances. Not surprisingly, pharmacokinetic-pharmacodynamic modeling concepts are increasingly applied in both basic and clinical research as well as in drug development. Fundamentals of Antimicrobial Pharmacokinetics and Pharmacodynamics is designed as a reference on the application of pharmacokinetic-pharmacodynamic principles for the optimization of antimicrobial therapy, namely pharmacotherapy, and infectious diseases. The reader is introduced to various aspects of the fundamentals of antimicrobial pharmacodynamics, the integration of pharmacokinetics with pharmacodynamics for all major classes of antibiotics, from basic research to clinical situations.
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Other form: | Print version: Fundamentals of antimicrobial pharmacokinetics and pharmacodynamics 9780387756127
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Standard no.: | 10.1007/978-0-387-75613-4
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