Metal-catalyzed asymmetric epoxidation and its related reactions /
Saved in:
Author / Creator: | Luo, Lan, author. |
---|---|
Imprint: | 2016. Ann Arbor : ProQuest Dissertations & Theses, 2016 |
Description: | 1 electronic resource (309 pages) |
Language: | English |
Format: | E-Resource Dissertations |
Local Note: | School code: 0330 |
URL for this record: | http://pi.lib.uchicago.edu/1001/cat/bib/10862905 |
LEADER | 02854ntm a22004333i 4500 | ||
---|---|---|---|
001 | 10862905 | ||
003 | ICU | ||
005 | 20161201094745.3 | ||
006 | m o d | ||
007 | cr un|---||||| | ||
008 | 160729s2016 miu|||||om |||||||eng d | ||
020 | |a 9781339874357 | ||
035 | |a (MiAaPQD)AAI10129544 | ||
035 | |a AAI10129544 | ||
040 | |a MiAaPQD |b eng |c MiAaPQD |e rda | ||
100 | 1 | |a Luo, Lan, |e author. | |
245 | 1 | 0 | |a Metal-catalyzed asymmetric epoxidation and its related reactions / |c Luo, Lan. |
260 | |c 2016. | ||
264 | 1 | |a Ann Arbor : |b ProQuest Dissertations & Theses, |c 2016 | |
300 | |a 1 electronic resource (309 pages) | ||
336 | |a text |b txt |2 rdacontent | ||
337 | |a computer |b c |2 rdamedia | ||
338 | |a online resource |b cr |2 rdacarrier | ||
500 | |a Advisors: Hisashi Yamamoto Committee members: Sergey Kozmin; Viresh Rawal. | ||
502 | |b Ph.D. |c University of Chicago, Division of the Physical Sciences, Department of Chemistry |d 2016. | ||
510 | 4 | |a Dissertation Abstracts International, |c Volume: 77-10(E), Section: B. | |
520 | |a Many important problems remain to be solved in catalytic asymmetric epoxidation, despite substantial progress in the past three decades. We drew our inspirations from the reactivity of metalloenzymes such as cytochrome P-450 and vanadium haloperoxidase, which perform some of the most difficult chemical transformations. Through carefully designed ancillary ligands, we have achieved asymmetric epoxidation and related functionalizations on a broad scope of substrates to afford products that were previously difficult to access. | ||
520 | |a This dissertation will include 1) iron-phenanthroline catalyzed asymmetric epoxidation of alpha, beta-unsaturated esters; 2) tandem enantioselective epoxidation and ring-opening kinetic resolution for the synthesis of virtually enantiopure aminodiols; and 3) synthetic studies towards (+)-catharanthine. | ||
546 | |a English | ||
590 | |a School code: 0330 | ||
690 | |a Organic chemistry. | ||
710 | 2 | |a University of Chicago. |e degree granting institution. | |
720 | 1 | |a Hisashi Yamamoto |e degree supervisor. | |
856 | 4 | 0 | |u http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqm&rft_dat=xri:pqdiss:10129544 |y ProQuest |
856 | 4 | 0 | |u http://dx.doi.org/10.6082/M1FQ9TJM |y Knowledge@UChicago |
929 | |a eresource | ||
999 | f | f | |i bd539056-8e21-5a71-965e-426b5d57e260 |s 5d4e9357-0a57-5e38-9a64-97b6c6df4ac7 |
928 | |t Library of Congress classification |l Online |c UC-FullText |u http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqm&rft_dat=xri:pqdiss:10129544 |z ProQuest |g ebooks |i 9267003 | ||
928 | |t Library of Congress classification |l Online |c UC-FullText |u http://dx.doi.org/10.6082/M1FQ9TJM |z Knowledge@UChicago |g ebooks |i 9371890 |