Contribution of the host's microbiota to retroviral transmission and pathogenesis /
Saved in:
| Author / Creator: | Wilks, Jessica, author. |
|---|---|
| Imprint: | 2015. Ann Arbor : ProQuest Dissertations & Theses, 2015 |
| Description: | 1 electronic resource (125 pages) |
| Language: | English |
| Format: | E-Resource Dissertations |
| Local Note: | School code: 0330 |
| URL for this record: | http://pi.lib.uchicago.edu/1001/cat/bib/10773303 |
MARC
| LEADER | 00000ntm a22000003i 4500 | ||
|---|---|---|---|
| 001 | 10773303 | ||
| 005 | 20230627204750.8 | ||
| 007 | cr un|---||||| | ||
| 008 | 151222s2015 miu||||||m |||| ||eng d | ||
| 003 | ICU | ||
| 020 | |a 9781339080901 | ||
| 035 | |a (MiAaPQD)AAI3724569 | ||
| 040 | |a MiAaPQD |b eng |c MiAaPQD |e rda | ||
| 100 | 1 | |a Wilks, Jessica, |e author. | |
| 245 | 1 | 0 | |a Contribution of the host's microbiota to retroviral transmission and pathogenesis / |c Wilks, Jessica. |
| 260 | |c 2015. | ||
| 264 | 1 | |a Ann Arbor : |b ProQuest Dissertations & Theses, |c 2015 | |
| 300 | |a 1 electronic resource (125 pages) | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 500 | |a Advisors: Tatyana Golovkina Committee members: Sasha Chervonsky; Sean Crosson; Howard Shuman. | ||
| 502 | |b Ph.D. |c The University of Chicago, Division of the Biological Sciences and Pritzker School of Medicine, Department of Microbiology |d 2015. | ||
| 506 | |a This item is not available from ProQuest Dissertations & Theses. | ||
| 510 | 4 | |a Dissertation Abstracts International, |c Volume: 77-02(E), Section: B. | |
| 520 | |a My dissertation explores the contribution of commensal bacteria to retroviral transmission and pathogenesis. I have found that commensal bacteria do not contribute to the anti-retroviral humoral response. In addition, I have found that a enveloped retrovirus exploits the host membrane proteins, CD14, LBP, MD2, and TLR4 to bind commensal LPS and subvert the antiviral immune response. Finally, I have found that commensal bacteria are required for retrovirally-induced leukemia. | ||
| 546 | |a English | ||
| 590 | |a School code: 0330 | ||
| 690 | |a Microbiology. | ||
| 710 | 2 | |a University of Chicago. |e degree granting institution. | |
| 720 | 1 | |a Tatyana Golovkina |e degree supervisor. | |
| 856 | 4 | 0 | |u http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqm&rft_dat=xri:pqdiss:3724569 |y ProQuest |
| 035 | |a AAI3724569 | ||
| 929 | |a eresource | ||
| 999 | f | f | |i 55d68cdb-ef49-547c-8579-f32544ffc23e |s 10b094c8-b861-52db-b968-4def0f352091 |
| 928 | |t Library of Congress classification |l Online |c UC-FullText |u http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqm&rft_dat=xri:pqdiss:3724569 |z ProQuest |i 9079530 | ||